Gilbert Schlewer: search on Z-Library

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1

Dérivés alkylés et arylés de l'acide nipécotique: synthèse et appréciation de l'activité inhibitrice de la capture du GABA en fonction de paramètres conformationnels et de biodisponibilité

Gérard Lapuyade, Gilbert Schlewer, Victor N'Goka, Jean-Claude Vernieres, Jean-Pierre Chambon, Jeanine Lagrange, Philippe Lagrange, Camille Georges Wermuth

Journal:

European Journal of Medicinal Chemistry

Year:

1987

File:

PDF, 1.10 MB

1987

2

GABA-uptake inhibitors: construction of a general pharmacophore model and successful prediction of a new representative

N'Goka, Victor, Schlewer, Gilbert, Linget, Jean Michel, Chambon, Jean Pierre, Wermuth, Camille Georges

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 1.37 MB

english, 1991

3

Synthesis of (±) Cyclohexane-1 (R),2 (R),4 (R)-Triol-Triphosphate, a Deoxygenated Analog of myo-Inositol -1,4,5- Triphosphate

Laurent Schmitt, Bernard Spiess, Gilbert Schlewer

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 204 KB

english, 1992

4

Synthesis of arylalkylmonofluorophosphonates as myo-inositol monophosphatase ligands

Laurent Schmitt, Nukhet Cavusoglu, Bernard Spiess, Gilbert Schlewer

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

5

Synthesis, Potentiometric and 31 P-NMR Investigations of the Ionization State and Complexation Properties of Inositol-Phosphates : Biological Consequences

Schmitt, Laurent, Bortmann, Patrick, Spiess, Bernard, Schlewer, Gilbert

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1993

Language:

english

File:

PDF, 207 KB

english, 1993

6

Syntheses and GABA Uptake Properties of 6-Ether- and 6-Enol Ether-Substituted Nipecotic Acids.

Victor N'Goka, Caterina Bissantz, Philippe Bisel, Tine B. Stenboel, Povl Krogsgaard-Larsen, Gilbert Schlewer

Journal:

Year:

2004

File:

PDF, 23 KB

2004

7

Total syntheses of chiral sn-myo-inositol-1,4,5-trisphosphate1 and its enantiomer

Alexander E. Stepanov, Olga B. Runova, Gilbert Schlewer, Bernard Spiess, Vitaly I. Shvets

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 237 KB

english, 1989

8

Allergic contact dermatitis due to sesquiterpene lactones : A COMPARATIVE STUDY OF HUMAN AND ANIMAL SENSITIVITY TO α-METHYLENE-γ-BUTYROLACTONE AND DERIVATIVES

JEAN-LUC STAMPF, GILBERT SCHLEWER, GEORGES DUCOMBS, JEAN FOUSSEREAU, CLAUDE BENEZRA

Journal:

British Journal of Dermatology

Year:

1978

Language:

english

File:

PDF, 2.01 MB

english, 1978

9

Complete Resolution of the Microscopic Protonation Equilibria of D-myo-Inositol 1,2,6-Tris(phosphate) and Related Compounds by 31P NMR and Potentiometry

Mernissi-Arifi, Khalid., Schmitt, Laurent., Schlewer, Gilbert., Spiess, Bernard.

Journal:

Analytical Chemistry

Year:

1995

Language:

english

File:

PDF, 847 KB

english, 1995

10

Synthesis of (±) 3,6-di-O-benzyl-2-myo-inosose 1,4,5-tri-O-dibenzylphosphate as potential intermediate for the preparation of tritium-labelled myo-inositol 1,4,5-triphosphate

Nathalie Schnetz-Boutaud, Bernard Spiess, Gilbert Schlewer

Journal:

Carbohydrate Research

Year:

1994

Language:

english

File:

PDF, 423 KB

english, 1994

11

Inframolecular Protonation Process of myo -Inositol 1,4,5-Tris(phosphate) and Related Compounds: Dynamics of the Intramolecular Interactions and Evidence of C−H···O Hydrogen Bonding

Felemez, Marc, Bernard, Philippe, Schlewer, Gilbert, Spiess, Bernard

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 165 KB

english, 2000

12

myo-Inositol 1,4,5-triphosphate and related compounds? protonation sequence: potentiometric and 31P NMR studies

Schmitt, Laurent, Bortmann, Patrick, Schlewer, Gilbert, Spiess, B.

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1993

Language:

english

File:

PDF, 896 KB

english, 1993

13

Complexation studies on inositol-phosphates: IV. Ca(II) complexes of myo-inositol 1,4,5-trisphosphate

Laurent Schmitt, Gilbert Schlewer, Bernard Spiess

Journal:

Journal of Inorganic Biochemistry

Year:

1992

Language:

english

File:

PDF, 390 KB

english, 1992

14

Inframolecular studies of the protonation of 1d-1,2,4/3,5-cyclopentanepentaol 1,3,4-trisphosphate, a ring-contracted analogue of 1d-myo-inositol 1,4,5-trisphosphate

Marc Felemez, Gilbert Schlewer, David J. Jenkins, Vanessa Correa, Colin W. Taylor, Barry V.L. Potter, Bernard Spiess

Journal:

Carbohydrate Research

Year:

1999

Language:

english

File:

PDF, 125 KB

english, 1999

15

myo -Inositol 1,4,5,6-Tetrakisphosphate and myo -Inositol 3,4,5,6-Tetrakisphosphate, Two Second Messengers that May Act as pH-Dependent Molecular Switches [ J. Am. Chem. Soc. 2001 , 123 , 3399−4000].

Blum-Held, Corinne, Bernard, Philippe, Schlewer, Gilbert, Spiess, Bernard

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 7 KB

english, 2001

16

Animal and human sensitivity to α-methylene-γ-butyrolactone derivatives

Jean-Luc Stampf, Gilbert Schlewer, Claude Benezra

Journal:

Contact Dermatitis

Year:

1978

File:

PDF, 197 KB

1978

17

A Conformationally Restricted Cyclic Phosphate Analogue of Inositol Trisphosphate: Synthesis and Physicochemical Properties

Riley, Andrew M., Guédat, Philippe, Schlewer, Gilbert, Spiess, Bernard, Potter, Barry V. L.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

18

Synthesis of Triazolo- and Tetrazoloquinoline Derivatives with Antithrombotic Activity

Schlewer, Gilbert, Desos, Patrice, Georges Wermuth, Camille

Journal:

Year:

1989

Language:

english

File:

PDF, 375 KB

english, 1989

19

Quantitative investigation of the interactions between inositol-tris(phosphates) and polyamines

Mernissi-Arifi, Khalid, Zenkouar, Mohamed, Schlewer, Gilbert, Spiess, Bernard

Journal:

Journal of the Chemical Society Faraday Transactions

Year:

1996

Language:

english

File:

PDF, 817 KB

english, 1996

20

6-(4-Phenyl-benzyloxy-methyl) guvacine. Synthesis, GABA uptake inhibitor and muscarinic properties

Philippe Bisel, Jean Pierre Gies, Gilbert Schlewer, Camille G. Wermuth

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 170 KB

english, 1996

21

3-Aminopyridazine derivatives with atypical antidepressant, serotonergic and dopaminergic activities

Wermuth, Camille Georges, Schlewer, Gilbert, Bourguignon, Jean Jacques, Maghioros, Georges, Bouchet, Marie Jeanne, Moire, Claudine, Kan, Jean Paul, Worms, Paul, Biziere, Kathleen

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 1.18 MB

english, 1989

22

Syntheses and GABA uptake properties of 6-ether- and 6-enol ether-substituted nipecotic acids

Victor N’Goka, Caterina Bissantz, Philippe Bisel, Tine B. Stenbøl, Povl Krogsgaard-Larsen, Gilbert Schlewer

Journal:

European Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 214 KB

english, 2004

23

Synthesis of 1-O-(2-oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol and 3,5-dideoxy-1-O-(2-oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol as prodrugs of inositolmonophosphatase ligands

Laurent Schmitt, Bernard Spiess, Gilbert Schlewer

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 200 KB

english, 1998

24

Rapid synthesis and properties of (±)-6-Deoxy-6-fluoro-myo-inositol-1,4,5-tris(phosphate) an analogue of myo-inositol-1,4,5-tris(phosphate)

Philippe Guédat, Marc Poitras, Bernard Spiess, Gaetan Guillemette, Gilbert Schlewer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 181 KB

english, 1996

25

Synthesis of .alpha.-methylene-.gamma.-butyrolactones: a structure-activity relationship study of their allergenic power

Schlewer, Gilbert, Stampf, Jean Luc, Benezra, Claude

Journal:

Journal of Medicinal Chemistry

Year:

1980

Language:

english

File:

PDF, 721 KB

english, 1980

26

Synthesis of (±)-2- O -[4‘-( N -9‘ ‘-Purinyl)butyl] myo -Inositol 1,4,5-Tris(phosphate), a Potent Full Agonist at the d - myo -Inositol 1,4,5-Tris(phosphate) Receptor

Moris, Marc-Antoine, Caron, Annabelle Z., Guillemette, Gaétan, Rognan, Didier, Schmitt, Martine, Schlewer, Gilbert

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 135 KB

english, 2005

27

Synthesis of and allergic contact dermatitis to bicyclo-[2,2,1]-heptyl-α-methylene-γ-butyrolactones derived from norbornene and camphene

Schlewer, Gilbert, Stampf, Jean-Luc, Benezra, Claude

Journal:

Canadian Journal of Biochemistry

Year:

1978

Language:

english

File:

PDF, 370 KB

english, 1978

28

Synthesis of (±) 1,2-dideoxy-1,2-diamino-myo-inositol

Philippe Guédat, Bernard Spiess, Gilbert Schlewer

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 204 KB

english, 1994

29

Inframolecular acid–base studies of the tris and tetrakis myo-inositol phosphates including the 1,2,3-trisphosphate motif

Hélène Dozol, Corinne Blum-Held, Philippe Guédat, Clarisse Maechling, Steve Lanners, Gilbert Schlewer, Bernard Spiess

Journal:

Journal of Molecular Structure

Year:

2002

Language:

english

File:

PDF, 171 KB

english, 2002

30

Synthesis of (±) myo-inositol-1-O-methylphosphonate-4,5-bis(phosphate), an analogue of D-Myo-inositol-1,4,5-tris(phosphate).

Laurent Schmitt, Bernard Spiess, Gilbert Schlewer

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 127 KB

english, 1993

31

INFRAMOLECULAR PROTONATION STUDIES OF 5-DEOXY-5,5-DIFLUORO- MYO -INOSITOL-1,2,6-TRIS(PHOSPHATE)

Ballereau, Stéphanie, Schlewer, Gilbert, Spiess, Bernard

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1997

Language:

english

File:

PDF, 230 KB

english, 1997

32

Investigation of the inframolecular acid–base properties of d-myo-inositol 1,3,4,5-tetrakisphosphate and dl-myo-inositol 1,2,4,5-tetrakisphosphate

Guédat, Philippe, Schlewer, Gilbert, Krempp, Elisabeth, Riley, Andrew M., Potter, Barry V. L., Spiess, Bernard

Journal:

Chemical Communications

Year:

1997

Language:

english

File:

PDF, 77 KB

english, 1997

33

Complexation of spermine and spermidine by myo-inositol 1,4,5-tris(phosphate) and related compounds: biological significance

Khalid Mernissi-Arifi, Isabelle Imbs, Gilbert Schlewer, Bernard Spiess

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1996

Language:

english

File:

PDF, 771 KB

english, 1996

34

Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists

Melikian, Anita, Schlewer, Gilbert, Chambon, Jean Pierre, Wermuth, Camille Georges

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.26 MB

english, 1992

35

Synthesis of optically active (+)-D-3,4,5-tri O-phenylcarbamoyl Myo-inositol from phytic acid

Corinne Blum, Susanne Karlsson, Gilbert Schlewer, Bernard Spiess, Nicola Rehnberg

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 156 KB

english, 1995

36

Allergic contact dermatitis to α-methylene-γ-butyrolactones: Preparation of alantolactone-protein conjugates and induction of contact sensitivity in the guinea pig by an alantolactone-skin protein conjugate

Gilles Dupuis, Claude Benezra, Gilbert Schlewer, Jean-Luc Stampf

Journal:

Molecular Immunology

Year:

1980

Language:

english

File:

PDF, 778 KB

english, 1980

37

Inframolecular protonation process of 6-modified myo-inositol 1,4,5-tris(phosphates): substitution effects on the cooperativity between the phosphate groups

Felemez, Marc, Ballereau, Ste´phanie, Schlewer, Gilbert, Spiess, Bernard

Journal:

New Journal of Chemistry

Year:

2000

Language:

english

File:

PDF, 207 KB

english, 2000

38

Synthesis of myo-inositol 4,6-cyclic,1,5-trisphosphate, a conformationally restricted analogue of myo-inositol 1,4,5-trisphosphate

Ballereau, Stéphanie, Poirier, Stéphane N., Guillemette, Gaetan, Spiess, Bernard, Schlewer, Gilbert

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

39

Synthesis and binding properties of cyclopentane analogues of myo-inositol 1,4,5-tris(phosphate)

Marc-Antoine Moris, Annabelle Z Caron, Gaétan Guillemette, Gilbert Schlewer

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 324 KB

english, 2004

40

Syntheses De γ, γ-Dimethyl α-Methylene-γ- Butyrolactone Et d'oxa-1 Spiro [4,5] Methylene-3 Decanone-2 Marquees Au Carbone-14

Gilbert Schlewer, Jean-Luc Stampf, Claude Benezra

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1980

File:

PDF, 249 KB

1980

41

Synthesis of (±)-4-deoxy-4-fluoro-myo-inositol

Stéphanie Ballereau, Philippe Guédat, Bernard Spiess, Nicola Rehnberg, Gilbert Schlewer

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 137 KB

english, 1995

42

Inframolecular acid–base properties of myo-inositol 1,2,6-trisphosphate analogues: influence of the hydroxyl groups, phosphate configuration and intracyclic atom substitution

Khalid Mernissi-Arifi, Gilbert Schlewer, Bernard Spiess

Journal:

Carbohydrate Research

Year:

1998

Language:

english

File:

PDF, 248 KB

english, 1998

43

Alantolactone in chrysanthemum extract

Claude Benezra, Gilbert Schlewer, Jean-Luc Stampf

Journal:

Contact Dermatitis

Year:

1978

File:

PDF, 212 KB

1978

44

Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of .gamma.-aminobutyric acid acting as selective GABA-A antagonists

Wermuth, Camille Georges, Bourguignon, Jean Jacques, Schlewer, Gilbert, Gies, Jean Pierre, Schoenfelder, Angele, Melikian, Anita, Bouchet, Marie Jeanne, Chantreux, Dominique, Molimard, Jean Charles

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 1.44 MB

english, 1987

45

C- or O-Alkylation of 5-Ethoxycarbonyl-2-Hydroxymethyl Pyridine with Arylmethane Derivatives

Bissantz, Caterina, Bisel, Philippe, Schlewer, Gilbert

Journal:

Year:

1998

Language:

english

File:

PDF, 23 KB

english, 1998

46

Synthesis, Acid−Base Behavior, and Binding Properties of 6-Modified myo -Inositol 1,4,5-Tris(phosphate)s

Ballereau, Stéphanie, Guédat, Philippe, Poirier, Stéphane N., Guillemette, Gaétan, Spiess, Bernard, Schlewer, Gilbert

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 302 KB

english, 1999

47

SYNTHESIS OF 5-DEOXY-5,5-DIFLUORO- MYO -INOSITOL-1,2,6-TRIS(PHOSPHATE)

Ballereau, Stephanie, Spiess, Bernard, Schlewer, Gilbert

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1997

Language:

english

File:

PDF, 372 KB

english, 1997

48

Synthesis and GABA uptake inhibitory properties of 6-aryl iminoxymethyl substituted nipecotic acids

Victor N'Goka, Tine B. Stenbøl, Povl Krogsgaard-Larsen, Gilbert Schlewer

Journal:

European Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 244 KB

english, 2004

49

Synthesis of optically active myo-inositol derivatives starting from phytic acid

Corinne Blum, Nicola Rehnberg, Bernard Spiess, Gilbert Schlewer

Journal:

Carbohydrate Research

Year:

1997

Language:

english

File:

PDF, 507 KB

english, 1997

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